Donor egg success rates over 45
“How woman age may impact the donor egg IVF success rate?”, “What are the challenges that a woman over 45 expect to have via IVF+ egg donation procedure?”, “How it could be possible I be pregnant at 46 with donor eggs?”, “What is donor egg success rates over 50” and the other questions that may occupy the mind of women want to going through treatments using IVF and donor egg!
Risk of pregnancy with own eggs over 45 | Age-affected factors
Unfortunately, there are two main factors that play a key role in the difficulty of conceiving in women over 45:
1. Diminishing ovarian reserves by age
“Ovarian reserves” term comes from the quality and number of eggs (oocytes) that have a direct relation to age. As reported by researchers, the average number of eggs at birth is about 2 million oocytes. Around age 37, the number of oocytes reaches 25,000. If the number and quality of eggs be less than anticipated for your age, diminished ovarian reserves are diagnosed.
In such cases, there is the most incredible opportunity; a donor egg will be proposed to the mother if the woman’s body is in good condition, and she could get pregnant and carry the baby. When a woman is incapable of carrying the embryo, a surrogacy procedure will be the next option!
2. Aneuploidy rates by age (Genetic disorders)
When one or more extra copies or missing chromosomes occur, an unbalance chromosome complement will result in genetic disorders and a condition called aneuploidy. Down Syndrome, known as trisomy 21, is the most famous case of aneuploidy, a widespread example due to an extra copy of chromosome 21.
The bad news is as a woman ages, the chances of having a baby with a chromosomal aneuploidy will increase. It's because the woman's egg age is the same as hers. Females are born with all their eggs, so it seems natural that, over time, problems may occur in the chromosomal division of the egg. Not properly dividing will produce extra or missing chromosomes in the egg.
Based on recent research, the risk of aneuploidy follows such figures:
• If the mom's age at delivery is 38, the risk of aneuploidy will be 1 in 102.
• If the mom's age at delivery is 40, the risk of aneuploidy will be 1 in 66.
• If the mom's age at delivery is 45, the risk of aneuploidy will be 1 in 21.
• If the mom's age at delivery is 49, the risk of aneuploidy will be 1 in 8.
Most embryos with own eggs of the mother in age 35-39 have a chance of abnormality of more than 45% and generally couldn't implant to the uterus. Females over 40 will experience a worse situation, and the embryo abnormality percentage will reach 50%.
Neglecting the above factors will push you the wrong way, and you will experience failed IVF cycles! When your fertility specialist advises the egg donation process, it is intellectual that you approve of their advice. It is better to avoid unnecessary insistence on using your egg and imposing unnecessary expenses on your family.
It is better to avoid unnecessary insistence on using your egg and imposing unnecessary expenses on your family.
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