IUI and IVF Side Effects

You should visit a doctor after a year of trying to have a child and not getting pregnant. If you are a woman over 35 or you have an irregular menstrual cycle, you should see a doctor after 6 months. The most common reason for infertility among women is the ovulation problem and the most common reason for infertility among men is a problem with sperm cells and their function.

Assisted reproductive technology (ART) can treat infertility problems in couples. All around the world, more than 3 million babies have been born with the help of in vitro fertilization (IVF). Also, other treatments like IUI are helping couples who seek parenthood. Both procedure cycles take about 2 weeks, but what is the exact difference between IUI and IVF? What are IUI and IVF side effects? If you are interested to know them better, be with us until the end of the article.


Quick Information



Duration of procedure

Hospital Stay

Minimum Stay in Iran

$4600 (IVF+PGD)


3-4 weeks

Zero day

3-4 weeks

IVF + Embryo Transfer

21-28 days
  • Treatment
  • Medical consultation
  • Post Treatment follow-up
  • Airport Pick up/Drop off
  • And more


21-28 days
  • Treatment
  • Medical consultation
  • Post Treatment follow-up
  • Airport Pick up/Drop off
  • And more

IVF + Egg Donation

21-28 days
  • Treatment
  • Medical consultation
  • Post Treatment follow-up
  • Airport Pick up/Drop off
  • And more

IVF + PGD + Egg Donation

21-28 days
  • Treatment
  • Medical consultation
  • Post Treatment follow-up
  • Airport Pick up/Drop off
  • And more

What is IUI?


Intrauterine Insemination (IUI) sometimes known as “artificial insemination” is one of the assisted reproductive technologies that facilitates insemination by putting sperms inside the woman’s uterus. IUI is a non-surgical, outpatient procedure that enhances the chance of insemination by increasing the sperm quantity that gets to the fallopian tubes, and automatically the chance of fertilization goes higher.

Of course, the sperm should reach and fertilize the egg on its own, but this method is less invasive and less expensive compared to IVF. It is recommended to use IUI treatment before trying IVF, especially for those couples who have male factor infertility like low sperm count, weak sperm movement, or those who are going to use donor sperm. IUI procedure is simple. Here are the main steps:

  1. Identifying the ovulation time for choosing the fertile period
  2. Collecting and washing semen
  3. Directly inserting sperm into the uterus

In this procedure, the doctor inserts the catheter into the cervix through the vagina. Then pushes the catheter through the cervical canal and points it to the top of the uterus, and finally, the sperm is injected into the uterus.

What is IVF?


In vitro fertilization (IVF) is the most common form of the assisted reproductive technology that has helped so many couples around the world. In this procedure, a female patient’s eggs are retrieved from the ovaries and are fertilized by the male partner’s sperm in a laboratory environment (in the Latin language, “in vitro” means in glass, which refers to the fertilization process in a laboratory glass dish). Then the resulting embryo or embryos are implanted into the uterus hoping to lead to a pregnancy. Along with IVF, other infertility treatment technologies can also be used including IVF+PGD and IVF+ICSI.

Due to bypassing fallopian tubes, this procedure is especially useful for patients who have blocked or damaged tubes or lack having it. Even in severe cases of male infertility, IVF only needs one sperm cell for fertilizing each egg. IVF is the most successful treatment for all forms of infertility including unexplained infertility and age-related infertility.

Advantages of IUI

As we mentioned before, IUI is an outpatient cycle of assisted reproductive treatment. There are some advantages regarding this procedure:

  • It is less invasive
  • It is cheaper than IVF or ICSI
  • There would be less stress on the body
  • The chance of success in IUI treatment is higher than regular sexual intercourse
  • The IUI procedure is not painful and does not need anesthesia
  • The procedure can be done with or without the guidance of transvaginal ultrasound
  • Washing the sperms enhances their quality by removing prostaglandins, infection, antigenic proteins, non-motile sperms, immature sperm cells, etc. Washing sperms also decreases the formation of free oxygen radicals.

Side Effects of IUI

Even though the IUI procedure has so many advantages and can be a great choice for many couples, it cannot solve all the fertility challenges. There are some side effects related to the IUI technique:

  • The female partner needs to be ovulating
  • Sperm must have a certain mobility level to get to the egg and fertilize it
  • The success rate of IUI when is combined with medication is around 20 to 25 percent
  • Because of taking fertility drugs, the risk of having multiple pregnancies increases

Fertility drugs can have side effects. These medications are used to stimulate ovaries to produce multiple oocytes but they may cause side effects like mood swings, breast tenderness, hot flushes, bloating, nausea, headache, painful and swollen ovaries, etc. however, these side effects will disappear after stopping the medication.

Advantages of IVF

IVF can be the best solution for couples who are suffering from infertility, same-sex couples, or those who cannot get pregnant naturally because of the removal of fallopian tubes. Here we are going to name the summarized advantages of IVF:

  • IVF works on many couples where other infertility treatments fail
  • IVF can be used for everyone
  • Using donor eggs and sperms is possible through IVF
  • You can control pregnancy timing
  • IVF increases the chances of having a healthy baby
  • IVF decreases the risks for miscarriage
  • It increases the chances of conception
  • IVF Provides the opportunity of screening in order to prevent genetic diseases through the use of PGD

IVF Provides the opportunity for gender selection when it is used along with PGD/PGS


Side Effects of IVF

Although IVF procedure is usually safe, there may be some potential side effects along with the benefits. Different reactions to the use of hormonal medications are the possible side effects of the IVF procedure. In addition, rare complications during egg retrieval and embryo transfer procedures can be named as the risks of the procedure.

Your fertility specialist tries to lessen the risks and make the procedure as safe as it could be. You should also talk with your fertility team if you see any severe side effects. The common IVF side effects are:

  • Nausea
  • Pain and bruise on injections spots
  • Breast tenderness
  • Bloating
  • Hot flashes
  • Mood swings
  • Fatigue
  • Allergic reactions
  • Loss of appetite
  • Ovarian hyperstimulation syndrome (OHSS)
  • Mild pelvic and abdominal pain
  • Pelvic infection
  • Multiple pregnancies
  • Emotional stress

If you ask people who have used the help of IVF technology, almost all of them would say that creating your family is worth the side effects of IVF. If you still concern about the side effects of this process, you can consult with our experts at TebMedTourism Co. to make your decision with high certainty.

Twins born trough ivf

Reducing Side Effects and Risks

We cannot avoid all the risks completely, but there are some ways to reduce the side effects. Good timing can reduce the medication’s side effects. Some side effects can be reduced when you take the medications at night or during your meal. You should ask your doctor about the best timing and the better way of taking the medications. The medications are better to be started with a low dose and be increased slowly if they did not go well.

To reduce the risks of multiple pregnancies, close monitoring of your cycle is important. Ultrasound technology can be used to identify the number of developing follicles that can be potential future babies. If the risk of multiple pregnancies is high for you, your doctor may terminate the cycle.

With the use of IVF, multiple pregnancies can be avoided if only one embryo be transferred to the uterus. Although this may not be an appropriate protocol for every couple.

You should know that even with careful monitoring and the help of a responsible doctor, you might still experience OHSS syndrome or have multiple pregnancies. The best thing to do is following your doctor’s orders carefully and have good personal care. However, OHSS rarely gets severe and you can usually deal with it at home.

You may like to read : IVF+ EGG DONATION + PGD IN IRAN

Author: Leila Nazari

Publisher and SEO specialist: beheshteh hadizadeh


About TebMedTourism company

TebMedTourism Company is an International healthcare facilitator based in Tehran, Iran.

We start our professional activity in medical tourism industry regarding the profound capability of Iran in both healthcare & touristic fields.

We are ready with open arms to provide desirable services to our dear patients & guests from all over the world to enjoy world-class treatment quality and highly skilled doctors in Iran.

TebMedTourism company is cooperating with more than 40 internationally certified hospitals, 140 selected local hospitals, 300 specialized medical centers, 430 doctors, 112 hotels, domestic and international airlines in Tehran, Shiraz, Mashhad, Tabriz, Qom and other cities in Iran.

TebMedTourism team facilitates comprehensive medical & cosmetic packages in all medical & wellness & touristic fields aimed to achieve your desires.

TebMedTourism experienced team will make this procedure seamless and enjoyable from A to Z, so you will just focus on your recovery.

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call us: +98 912 098 5010

Visit us: No.2, First 8 meter alley, Nobovvat sq., Tehran, Iran

Mail us: Tebmedtourism@gmail.com

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