ivf pgd

IVF-ET cycle

Infertility treatment options

IVF-ET cycle (complete cycle)

A couple planning a family expects things to take their natural course and for the woman to become pregnant within a few months of saying goodbye to contraception. For many couples, this is the case but one in six couples experiences difficulty conceiving a baby. After trying for several more months without success, fertility testing may or may not reveal an underlying problem that can be tackled. Infertility treatment is then worth careful consideration.

In this overview article, we look at the full range of infertility treatments available throughout the world; you can follow the links to more detailed articles elsewhere in the guide.

Infertility treatment for known fertility issues

This first category of treatments is the only one that is not classified as assisted reproduction. These infertility treatments aim to treat an underlying problem so that pregnancy can occur naturally:

  • Surgery to clear a woman’s blocked fallopian tubes: this is done by laparoscopy, and involves only small incisions in the abdomen. Once the tubes are clear, the eggs produced by the ovaries can travel more easily towards the uterus, and a natural pregnancy may be possible.
  • Hormone treatment to redress an imbalance: this treatment can work well in either partner. Thyroid problems and an imbalance of sex hormones can be corrected by taking artificial hormones.
  • Correction of an anatomical abnormality: this can include treating a large varicose vein in the testicle that may be blocking sperm release, or correcting retrograde ejaculation (in which the semen goes into the bladder during an orgasm, instead of through the penis).
  • Surgical sperm retrieval: various surgical methods can be used to extract sperm directly from the testes in men who produce no sperm in their semen. This is generally regarded as being part of assisted reproduction, as the sperm is then used in a cycle of in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI). IVF-ET cycle (complete cycle)
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IVF cost in Iran e1598168381930

IVF and Embryo Transfer cost in Iran

IVF + Egg Donation + PGD

21-28 days
$4900
  • Treatment
  • Medical consultation
  • Post Treatment follow-up
  • Airport Pick up/Drop off

IVF + PGD

21- 28 days
$4500
  • Treatment
  • Medical consultation
  • Post Treatment follow-up
  • Airport Pick up/Drop off

IVF + Egg Donation

21-28 days
$4300
  • Treatment
  • Medical consultation
  • Post Treatment follow-up
  • Airport Pick up/Drop off

IVF + Embryo Transfer

21- 28 days
$2400
  • Treatment
  • Medical consultation
  • Post Treatment follow-up
  • Airport Pick up/Drop off

In vitro fertilization – the most popular infertility treatment

In vitro fertilization (IVF) is now the most widely used infertility treatment in the world and has produced hundreds of thousands of new human beings, born to couples who would otherwise have been childless.

Standard in vitro fertilization involves stimulating the production of several eggs, collecting those eggs and mixing them with the partner’s sperm in the laboratory. A high proportion of the eggs are fertilized and embryos are then transferred back into the female partner’s uterus either after 2–3 days or after 5–6 days. IVF-ET cycle (complete cycle)

Different countries have different rules on the number of embryos that can be transferred; many are reducing this number to avoid the complication of multiple births.

Various IVF options are available:

  • Natural cycle IVF: no stimulating hormones are used, just the woman’s natural cycle.
  • Mild stimulation IVF: fewer hormones are used than in standard IVF.
  • In vitro maturation (IVM): eggs are collected in an immature form from the ovaries, which avoids the use of hormone stimulation but provides several eggs for IVF. The eggs are allowed to mature in culture before sperm is introduced to fertilize them.
  • IVF with fresh embryo transfer
  • IVF with frozen embryo transfer
  • IVF with blastocyst embryo transfer
  • IVF with assisted hatching (AH)this is done before transferring the embryo or blastocyst.

In vitro fertilization (IVF) has now become a phrase in such common use that it is rare for anyone to talk about ‘test tube babies’ any more. Babies born as a result of in vitro fertilization are born after being fertilized outside the mother’s body. In vitro means literally ‘in glass’ but most IVF cycles take place in laboratory-grade plastic these days.

IVF-ET cycle (complete cycle)

Why have in vitro fertilization?

This is the most commonly performed infertility treatment in the world. It can help the hundreds of thousands of couples worldwide who are unable to conceive naturally. Reasons for infertility vary, but IVF can help couples with both male and female infertility issues:

  • In vitro fertilization is the standard technique for women who have blocked fallopian tubes.
  • It is used in cases of male infertility, in which the man’s sperm is unable to fertilize his partner’s egg naturally, either because he has a very low sperm count, or his sperm is very poor swimmers.
  • In vitro fertilization can be used in conjunction with other techniques, such as intracytoplasmic sperm injection, if a man produces no sperm in his ejaculation. The sperm is surgically retrieved from his testes using one of several techniques.
  • IVF can be used to treat unexplained infertility. Even if no reason can be found to explain why a couple cannot have a baby naturally, a cycle of in vitro fertilization can still result in a successful pregnancy.
  • IVF-ET cycle (complete cycle)

The main process of in vitro fertilization

Procedures differ both between different countries, where regulations may not be the same, and between fertility clinics in the same country. There are also several types of in vitro fertilization that may increase success rates.

The entire in vitro fertilization cycle takes about 25 days to complete, and it usually commences on the third day of a natural period. It involves:

  • Two weeks of hormone treatment for the female partner to stop her going through her own normal menstrual cycle, as this would interfere with the preparations for in vitro fertilization. This involves having a daily injection or a nose spray of a hormone that acts on the pituitary gland to stop it producing sex hormones.
  • Hormone treatment with follicle stimulating hormone: this stimulates the ovaries to produce several eggs at once so that several embryos can be produced from the in vitro fertilization. This involves an injection each day, for 12 days.
  • Constant monitoring using blood tests and ultrasound: it is vital to check on the stage of egg production so they can be collected at their best. A different injection is given to mature the eggs about 36 hours before egg collection.
  • Sperm collection: the male partner will be asked to provide some fresh ejaculate about three hours before the eggs are collected. The sperm sample is washed and put in a high-speed centrifuge to help select the sperm that is active and healthy.
  • Egg collection: the female partner will be sedated while a needle, guided by ultrasound, is use to collect as many eggs as possible from both ovaries.
  • In vitro fertilisation: the eggs are mixed with the sperm in special culture fluid; fertilisation usually occurs within 24 hours.
  • Embryo culture: any eggs that have been fertilized are cultured for another 1–2 days and then checked. At that point, either the 2–3-day old embryos will be transferred into the woman’s uterus, or they will be cultured until day 5 or day 6 to see if any become blastocysts. Blastocyst embryo transfer can have a slightly higher success rate. Some fertility clinics favor assisted hatching before implanting the embryos.
  • Embryo or blastocyst transfer: depending on the woman’s age, between one and three embryos or blastocysts will be transferred.

A pregnancy test carried out about two weeks after embryo or blastocyst transfer reveals whether the cycle of in vitro fertilisation has been successful.

IVF-ET cycle (complete cycle)

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Success rates of in vitro fertilization

Success rates have been increasing and maybe a little higher if techniques such as blastocyst transfer or assisted hatching are used. Typically, though, the main factor that impacts on the success of in vitro fertilization is the age of the female partner. If she is under 35, each cycle of in vitro fertilization has a 32.3 % chance of achieving pregnancy. This declines to 27.2 % if she is between 35 and 37, to 19.2 % if she is a year older, between 38 and 39, and goes down to 1.5 % in women who are 45 or more.

IVF-ET cycle (complete cycle)

What if in vitro fertilization fails?

If you have one failed cycle, then you can try again after waiting for a month or so; the deciding factor in how many cycles of in vitro fertilization most couples can have is the financial cost. For couples in countries where the cost of private infertility treatment is high, many consider the options available in fertility clinics abroad, where the cost of an IVF cycle can be much lower.

Sadly, some couples go through the trauma of many failed cycles, spending all their savings, only to find that they are still unable to have a child. In this case, other options such as fostering, adoption or surrogacy may become important.

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The emotional impact of in vitro fertilization

By the time you embark on your first cycle of in vitro fertilization, you may well have been trying for a baby for several years, and you may already have had other infertility treatments. By this stage, couples can become quite obsessed with the need to get pregnant, and this can lead to relationship strain and isolation. It is important to understand the risks of in vitro fertilization, such as the potential for multiple pregnancies, and to realize what the success rate statistics mean. Having in vitro fertilization can never be stress-free, but it helps to have a realistic and flexible perspective.

IVF-ET cycle (complete cycle)

IVF-ET cycle (complete cycle) in Iran

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Embryo transfer is a simple procedure that follows in vitro fertilization (IVF) and is often considered the simplest and final step of the in the vitro fertilization process. The objective of embryo transfer is to facilitate conception following fertilization from the in vitro fertilization procedure.

When Does The Embryo Transfer Procedure Occur?

Embryos are generally transferred to the woman’s uterus at the 2-8 cell stage. Embryos may be transferred anytime between day 1 through day 6 after the retrieval of the egg, although it is usually between days 2-4. Some clinics are now allowing the embryo to reach blastocysts stage before transferring, which occurs around day 5.

IVF+PGD in Iran

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  1. Pingback: InfertilityTreatment In Iran , InfertilityTreatment Cost In Iran

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